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Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress

The long-term effect of exposure to DNA alkylating agents is entwined with the cell's genetic capacity for DNA repair and appropriate DNA damage responses. A unique combination of environmental exposure and deficiency in these responses can lead to genomic instability; this “gene–environment interac...

Täydet tiedot

Tallennettuna:
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Sobol, Robert W., Watson, David E., Nakamura, Jun, Yakes, F. Michael, Hou, Esther, Horton, Julie K., Ladapo, Joseph, Van Houten, Bennett, Swenberg, James A., Tindall, Kenneth R., Samson, Leona D., Wilson, Samuel H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2002
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124494/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11983862/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.092662499
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