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Subcellular distribution of Wnt pathway proteins in normal and neoplastic colon
Mutations in the APC tumor suppressor gene are present in approximately 85% of colorectal tumors and are thought to contribute early in the process of tumorigenesis. The truncated protein resulting from most APC mutations can lead to elevated β-catenin levels in colon tumor cells. APC and associated...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124359/ https://ncbi.nlm.nih.gov/pubmed/12072559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122235399 |
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