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Subcellular distribution of Wnt pathway proteins in normal and neoplastic colon

Mutations in the APC tumor suppressor gene are present in approximately 85% of colorectal tumors and are thought to contribute early in the process of tumorigenesis. The truncated protein resulting from most APC mutations can lead to elevated β-catenin levels in colon tumor cells. APC and associated...

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Autors principals: Anderson, Christine B., Neufeld, Kristi L., White, Raymond L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC124359/
https://ncbi.nlm.nih.gov/pubmed/12072559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122235399
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