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Synthetic LXR ligand inhibits the development of atherosclerosis in mice

The nuclear receptors LXRα and LXRβ have been implicated in the control of cholesterol and fatty acid metabolism in multiple cell types. Activation of these receptors stimulates cholesterol efflux in macrophages, promotes bile acid synthesis in liver, and inhibits intestinal cholesterol absorption,...

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Hlavní autoři:	Joseph, Sean B., McKilligin, Elaine, Pei, Liming, Watson, Michael A., Collins, Alan R., Laffitte, Bryan A., Chen, Mingyi, Noh, Grace, Goodman, Joanne, Hagger, Graham N., Tran, Jonathan, Tippin, Tim K., Wang, Xuping, Lusis, Aldons J., Hsueh, Willa A., Law, Ronald E., Collins, Jon L., Willson, Timothy M., Tontonoz, Peter
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	The National Academy of Sciences 2002
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.gov/pmc/articles/PMC124297/ https://ncbi.nlm.nih.gov/pubmed/12032330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.112059299
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Synthetic LXR ligand inhibits the development of atherosclerosis in mice

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