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Complex Inheritance of the 5-Lipoxygenase Locus Influencing Atherosclerosis in Mice
We previously mapped a locus on chromosome 6 with a large effect (LOD > 6) on aortic lesion size in a (C57BL/6J × CAST/Ei) F(2) cross and identified arachidonate 5-lipoxygenase (5LO) as a candidate gene in this region. Subsequent studies with the 5LO knockout model showed effects on atheroscleros...
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| Formaat: | Artigo |
| Taal: | Inglês |
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Copyright © 2006 by the Genetics Society of America
2006
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1526544/ https://ncbi.nlm.nih.gov/pubmed/16624897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.057455 |
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