Synthetic LXR ligand inhibits the development of atherosclerosis in mice

The nuclear receptors LXRα and LXRβ have been implicated in the control of cholesterol and fatty acid metabolism in multiple cell types. Activation of these receptors stimulates cholesterol efflux in macrophages, promotes bile acid synthesis in liver, and inhibits intestinal cholesterol absorption,...

Full description

Saved in:
Bibliographic Details
Main Authors: Joseph, Sean B., McKilligin, Elaine, Pei, Liming, Watson, Michael A., Collins, Alan R., Laffitte, Bryan A., Chen, Mingyi, Noh, Grace, Goodman, Joanne, Hagger, Graham N., Tran, Jonathan, Tippin, Tim K., Wang, Xuping, Lusis, Aldons J., Hsueh, Willa A., Law, Ronald E., Collins, Jon L., Willson, Timothy M., Tontonoz, Peter
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC124297/
https://ncbi.nlm.nih.gov/pubmed/12032330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.112059299
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items