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A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway

The eukaryotic intra-S-phase checkpoint, which slows DNA synthesis in response to DNA damage, is poorly understood. Is DNA damage recognized directly, or indirectly through its effects on replication forks? Is the slowing of S phase in part because of competition between DNA synthesis and recombinat...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Marchetti, Maria A., Kumar, Sanjay, Hartsuiker, Edgar, Maftahi, Mohamed, Carr, Antony M., Freyer, Greg A., Burhans, William C., Huberman, Joel A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124255/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12032307/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.112702399
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