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Cdc7–Drf1 is a developmentally regulated protein kinase required for the initiation of vertebrate DNA replication

Cdc7, a protein kinase required for the initiation of eukaryotic DNA replication, is activated by a regulatory subunit, Dbf4. A second activator of Cdc7 called Drf1 exists in vertebrates, but its function is unknown. Here, we report that in Xenopus egg extracts, Cdc7-Drf1 is far more abundant than C...

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Bibliografische gegevens
Hoofdauteurs: Takahashi, Tatsuro S., Walter, Johannes C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1240038/
https://ncbi.nlm.nih.gov/pubmed/16204181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1339805
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