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Cdc7–Drf1 kinase links chromosome cohesion to the initiation of DNA replication in Xenopus egg extracts

To establish functional cohesion between replicated sister chromatids, cohesin is recruited to chromatin before S phase. Cohesin is loaded onto chromosomes in the G1 phase by the Scc2–Scc4 complex, but little is known about how Scc2–Scc4 itself is recruited to chromatin. Using Xenopus egg extracts a...

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Main Authors: Takahashi, Tatsuro S., Basu, Abhijit, Bermudez, Vladimir, Hurwitz, Jerard, Walter, Johannes C.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492736/
https://ncbi.nlm.nih.gov/pubmed/18628396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1683308
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