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AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain
Recently, we described a 160 kDa protein (designated AS160, for Akt substrate of 160 kDa) with a predicted Rab GAP (GTPase-activating protein) domain that is phosphorylated on multiple sites by the protein kinase Akt. Phosphorylation of AS160 in adipocytes is required for insulin-stimulated transloc...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Portland Press Ltd.
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1237142/ https://ncbi.nlm.nih.gov/pubmed/15971998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050887 |
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