AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain

Recently, we described a 160 kDa protein (designated AS160, for Akt substrate of 160 kDa) with a predicted Rab GAP (GTPase-activating protein) domain that is phosphorylated on multiple sites by the protein kinase Akt. Phosphorylation of AS160 in adipocytes is required for insulin-stimulated transloc...

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Detalhes bibliográficos
Main Authors: Mîinea, Cristinel P., Sano, Hiroyuki, Kane, Susan, Sano, Eiko, Fukuda, Mitsunori, Peränen, Johan, Lane, William S., Lienhard, Gustav E.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237142/
https://ncbi.nlm.nih.gov/pubmed/15971998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050887
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