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Insulin-stimulated Phosphorylation of the Rab GTPase-activating Protein TBC1D1 Regulates GLUT4 Translocation

Insulin stimulates the translocation of the glucose transporter GLUT4 from intracellular locations to the plasma membrane in adipose and muscle cells. Prior studies have shown that Akt phosphorylation of the Rab GTPase-activating protein, AS160 (160-kDa Akt substrate; also known as TBC1D4), triggers...

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Bibliographische Detailangaben
Hauptverfasser: Peck, Grantley R., Chavez, Jose A., Roach, William G., Budnik, Bogdan A., Lane, William S., Karlsson, Håkan K. R., Zierath, Juleen R., Lienhard, Gustav E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781555/
https://ncbi.nlm.nih.gov/pubmed/19740738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.035568
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