Insulin-stimulated Phosphorylation of the Rab GTPase-activating Protein TBC1D1 Regulates GLUT4 Translocation

Insulin stimulates the translocation of the glucose transporter GLUT4 from intracellular locations to the plasma membrane in adipose and muscle cells. Prior studies have shown that Akt phosphorylation of the Rab GTPase-activating protein, AS160 (160-kDa Akt substrate; also known as TBC1D4), triggers...

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Detalhes bibliográficos
Main Authors: Peck, Grantley R., Chavez, Jose A., Roach, William G., Budnik, Bogdan A., Lane, William S., Karlsson, Håkan K. R., Zierath, Juleen R., Lienhard, Gustav E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781555/
https://ncbi.nlm.nih.gov/pubmed/19740738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.035568
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