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Insulin-stimulated GLUT4 Protein Translocation in Adipocytes Requires the Rab10 Guanine Nucleotide Exchange Factor Dennd4C

Insulin-stimulated translocation of the glucose transporter GLUT4 to the cell surface in fat and muscle cells is the basis for insulin-stimulated glucose transport. Studies in adipocytes strongly support the following molecular mechanism for this process. Insulin-elicited phosphorylation of the GTPa...

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Autors principals: Sano, Hiroyuki, Peck, Grantley R., Kettenbach, Arminja N., Gerber, Scott A., Lienhard, Gustav E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089496/
https://ncbi.nlm.nih.gov/pubmed/21454697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C111.228908
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