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A TrkA-to-p75(NTR) molecular switch activates amyloid β-peptide generation during aging
Aging is the single most important risk factor for AD (Alzheimer's disease). However, the molecular events that connect normal aging to AD are mostly unknown. The abnormal accumulation of Aβ (amyloid β-peptide) in the form of senile plaques is one of the main characteristics of AD. In the prese...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1237139/ https://ncbi.nlm.nih.gov/pubmed/15966860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050700 |
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