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Mapping the evolution of regional atrophy in Alzheimer's disease: Unbiased analysis of fluid-registered serial MRI

Alzheimer's disease (AD) is characterized by progressive cerebral atrophy, which may be assessed by using volumetric MRI. We describe a voxel-based analysis of nonlinear-registered serial MRI to demonstrate the most statistically significant (P < 0.001) regions of change at different stages...

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Detalhes bibliográficos
Main Authors: Scahill, Rachael I., Schott, Jonathan M., Stevens, John M., Rossor, Martin N., Fox, Nick C.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123711/
https://ncbi.nlm.nih.gov/pubmed/11930016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052587399
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