Genetic Influences on Atrophy Patterns in Familial Alzheimer’s Disease: A Comparison of APP and PSEN1 Mutations

Mutations in the presenilin1 (PSEN1) and amyloid β-protein precursor (APP) genes account for the majority of cases of autosomal dominantly inherited Alzheimer’s disease (AD). We wished to assess and compare the patterns of cerebral loss produced by these two groups of mutations. Volumetric magnetic...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Scahill, Rachael I., Ridgway, Gerard R., Bartlett, Jonathan W., Barnes, Josephine, Ryan, Natalie S., Mead, Simon, Beck, Jonathan, Clarkson, Matthew J., Crutch, Sebastian J., Schott, Jonathan M., Ourselin, Sebastien, Warren, Jason D., Hardy, John, Rossor, Martin N., Fox, Nick C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982537/
https://ncbi.nlm.nih.gov/pubmed/23380992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-121255
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