A Differentiation-dependent Splice Variant of Myosin Light Chain Kinase, MLCK1, Regulates Epithelial Tight Junction Permeability

Activation of Na(+)-nutrient cotransport leads to increased tight junction permeability in intestinal absorptive (villus) enterocytes. This regulation requires myosin II regulatory light chain (MLC) phosphorylation mediated by MLC kinase (MLCK). We examined the spatiotemporal segregation of MLCK iso...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Clayburgh, Daniel R., Rosen, Shari, Witkowski, Edwina D., Wang, Fengjun, Blair, Stephanie, Dudek, Steven, Garcia, Joe G. N., Alverdy, John C., Turner, Jerrold R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2004
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237105/
https://ncbi.nlm.nih.gov/pubmed/15507455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M408822200
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