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Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice

Rheumatoid arthritis is one of the most critical diseases that impair the quality of life of patients, but its pathogenesis has not yet been fully understood. Osteopontin (OPN) is an extracellular matrix protein containing Arg-Gly-Asp (RGD) sequence, which interacts with αvβ3 integrins, promotes cel...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Yumoto, Kenji, Ishijima, Muneaki, Rittling, Susan R., Tsuji, Kunikazu, Tsuchiya, Yoko, Kon, Shigeyuki, Nifuji, Akira, Uede, Toshimitsu, Denhardt, David T., Noda, Masaki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123686/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11930008/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.052523599
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