Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice

Rheumatoid arthritis is one of the most critical diseases that impair the quality of life of patients, but its pathogenesis has not yet been fully understood. Osteopontin (OPN) is an extracellular matrix protein containing Arg-Gly-Asp (RGD) sequence, which interacts with αvβ3 integrins, promotes cel...

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Detalles Bibliográficos
Autores principales: Yumoto, Kenji, Ishijima, Muneaki, Rittling, Susan R., Tsuji, Kunikazu, Tsuchiya, Yoko, Kon, Shigeyuki, Nifuji, Akira, Uede, Toshimitsu, Denhardt, David T., Noda, Masaki
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2002
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC123686/
https://ncbi.nlm.nih.gov/pubmed/11930008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052523599
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