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Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice
Rheumatoid arthritis is one of the most critical diseases that impair the quality of life of patients, but its pathogenesis has not yet been fully understood. Osteopontin (OPN) is an extracellular matrix protein containing Arg-Gly-Asp (RGD) sequence, which interacts with αvβ3 integrins, promotes cel...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The National Academy of Sciences
2002
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123686/ https://ncbi.nlm.nih.gov/pubmed/11930008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052523599 |
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