HLA class I-restricted responses to vaccinia recognize a broad array of proteins mainly involved in virulence and viral gene regulation

We have analyzed by ex vivo ELISPOT the anti-vaccinia cytotoxic T lymphocyte responses of peripheral blood mononuclear cells from humans vaccinated with Dryvax vaccine. More than 6,000 peptides from 258 putative vaccinia ORFs predicted to bind the common molecules of the HLA A1, A2, A3, A24, B7, and...

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Detalhes bibliográficos
Main Authors: Oseroff, Carla, Kos, Ferdynand, Bui, Huynh-Hoa, Peters, Bjoern, Pasquetto, Valerie, Glenn, Jean, Palmore, Tara, Sidney, John, Tscharke, David C., Bennink, Jack R., Southwood, Scott, Grey, Howard M., Yewdell, Jonathan W., Sette, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236582/
https://ncbi.nlm.nih.gov/pubmed/16172378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506768102
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