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Of mice and humans: how good are HLA transgenic mice as a model of human immune responses?
BACKGROUND: Previous studies have defined vaccinia virus (VACV)-derived T cell epitopes in VACV-infected human leukocyte antigen-A*0201 (HLA-A2.1) transgenic (Tg) mice and A2.1-positive human Dryvax vaccinees. A total of 14 epitopes were detected in humans and 16 epitopes in A2.1 Tg mice; however, o...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2702351/ https://ncbi.nlm.nih.gov/pubmed/19534819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-7580-5-3 |
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