Polyfunctional CD4(+ )T cell responses to a set of pathogenic arenaviruses provide broad population coverage

BACKGROUND: Several arenaviruses cause severe hemorrhagic fever and aseptic meningitis in humans for which no licensed vaccines are available. A major obstacle for vaccine development is pathogen heterogeneity within the Arenaviridae family. Evidence in animal models and humans indicate that T cell...

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Bibliographische Detailangaben
Hauptverfasser: Kotturi, Maya F, Botten, Jason, Maybeno, Matt, Sidney, John, Glenn, Jean, Bui, Huynh-Hoa, Oseroff, Carla, Crotty, Shane, Peters, Bjoern, Grey, Howard, Altmann, Daniel M, Buchmeier, Michael J, Sette, Alessandro
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880318/
https://ncbi.nlm.nih.gov/pubmed/20478058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-7580-6-4
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