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The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types

The misregulation of programmed cell death, or apoptosis, contributes to the pathogenesis of many diseases. We used Nomarski microscopy to screen for mutants containing refractile cell corpses in a C. elegans strain in which all programmed cell death is blocked and such corpses are absent. We isolat...

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Hlavní autoři: Hersh, Bradley M., Hartwieg, Erika, Horvitz, H. Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC123652/
https://ncbi.nlm.nih.gov/pubmed/11904372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062065399
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