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The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types

The misregulation of programmed cell death, or apoptosis, contributes to the pathogenesis of many diseases. We used Nomarski microscopy to screen for mutants containing refractile cell corpses in a C. elegans strain in which all programmed cell death is blocked and such corpses are absent. We isolat...

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Detalhes bibliográficos
Main Authors: Hersh, Bradley M., Hartwieg, Erika, Horvitz, H. Robert
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123652/
https://ncbi.nlm.nih.gov/pubmed/11904372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062065399
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