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Most Caenorhabditis elegans microRNAs Are Individually Not Essential for Development or Viability

MicroRNAs (miRNAs), a large class of short noncoding RNAs found in many plants and animals, often act to post-transcriptionally inhibit gene expression. We report the generation of deletion mutations in 87 miRNA genes in Caenorhabditis elegans, expanding the number of mutated miRNA genes to 95, or 8...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Miska, Eric A, Alvarez-Saavedra, Ezequiel, Abbott, Allison L, Lau, Nelson C, Hellman, Andrew B, McGonagle, Shannon M, Bartel, David P, Ambros, Victor R, Horvitz, H. Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134938/
https://ncbi.nlm.nih.gov/pubmed/18085825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030215
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