Most Caenorhabditis elegans microRNAs Are Individually Not Essential for Development or Viability

MicroRNAs (miRNAs), a large class of short noncoding RNAs found in many plants and animals, often act to post-transcriptionally inhibit gene expression. We report the generation of deletion mutations in 87 miRNA genes in Caenorhabditis elegans, expanding the number of mutated miRNA genes to 95, or 8...

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Detalhes bibliográficos
Main Authors: Miska, Eric A, Alvarez-Saavedra, Ezequiel, Abbott, Allison L, Lau, Nelson C, Hellman, Andrew B, McGonagle, Shannon M, Bartel, David P, Ambros, Victor R, Horvitz, H. Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134938/
https://ncbi.nlm.nih.gov/pubmed/18085825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030215
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