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Endogenous Production of Lipoic Acid Is Essential for Mouse Development

α-Lipoic acid (LA) is a cofactor for mitochondrial α-ketoacid dehydrogenase complexes and is one of the most potent, natural antioxidants. Reduction of oxidative stress by LA supplementation has been demonstrated in patients with diabetic neuropathy and in animal models. To determine how normal deve...

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Autori principali: Yi, Xianwen, Maeda, Nobuyo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234338/
https://ncbi.nlm.nih.gov/pubmed/16135825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.18.8387-8392.2005
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