H1 Linker Histones Are Essential for Mouse Development and Affect Nucleosome Spacing In Vivo

Most eukaryotic cells contain nearly equimolar amounts of nucleosomes and H1 linker histones. Despite their abundance and the potential functional specialization of H1 subtypes in multicellular organisms, gene inactivation studies have failed to reveal essential functions for linker histones in vivo...

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Autors principals: Fan, Yuhong, Nikitina, Tatiana, Morin-Kensicki, Elizabeth M., Zhao, Jie, Magnuson, Terry R., Woodcock, Christopher L., Skoultchi, Arthur I.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC164858/
https://ncbi.nlm.nih.gov/pubmed/12808097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.13.4559-4572.2003
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