H1 Linker Histones Are Essential for Mouse Development and Affect Nucleosome Spacing In Vivo

Most eukaryotic cells contain nearly equimolar amounts of nucleosomes and H1 linker histones. Despite their abundance and the potential functional specialization of H1 subtypes in multicellular organisms, gene inactivation studies have failed to reveal essential functions for linker histones in vivo...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Fan, Yuhong, Nikitina, Tatiana, Morin-Kensicki, Elizabeth M., Zhao, Jie, Magnuson, Terry R., Woodcock, Christopher L., Skoultchi, Arthur I.
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 2003
Subjects:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164858/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12808097/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.13.4559-4572.2003
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