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Endogenous Production of Lipoic Acid Is Essential for Mouse Development

α-Lipoic acid (LA) is a cofactor for mitochondrial α-ketoacid dehydrogenase complexes and is one of the most potent, natural antioxidants. Reduction of oxidative stress by LA supplementation has been demonstrated in patients with diabetic neuropathy and in animal models. To determine how normal deve...

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Detalhes bibliográficos
Main Authors: Yi, Xianwen, Maeda, Nobuyo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234338/
https://ncbi.nlm.nih.gov/pubmed/16135825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.18.8387-8392.2005
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