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Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice
Caveolins are important components of caveolae, which have been implicated in vesicular trafficking and signal transduction. To investigate the in vivo significance of Caveolins in mammals, we generated mice deficient in the caveolin-1 (cav-1) gene and have shown that, in the absence of Cav-1, no ca...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123264/ https://ncbi.nlm.nih.gov/pubmed/12177436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172360799 |
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