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Gene expression profiling of dilated cardiomyopathy in older male EP4 knockout mice

Using a line of mice with cardiac-specific knockout (KO) of the EP4 receptor gene, experiments were designed to determine whether a cardiac phenotype developed with age. Cardiac function was assessed by echocardiography in 23- to 33-wk-old male and female KO and littermate controls (WT) mice. After...

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Main Authors: Harding, Pamela, Yang, Xiao-Ping, Yang, James, Shesely, Ed, He, Quan, LaPointe, Margot C.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822585/
https://ncbi.nlm.nih.gov/pubmed/20008274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00746.2009
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