Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila

The tumor suppressor function of p53 has been attributed to its ability to regulate apoptosis and the cell cycle. In mammals, DNA damage, aberrant growth signals, chemotherapeutic agents, and UV irradiation activate p53, a process that is regulated by several posttranslational modifications. In Dros...

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Main Authors: Peters, Malte, DeLuca, Carmela, Hirao, Atsushi, Stambolic, Vuk, Potter, Julia, Zhou, Lily, Liepa, Jennifer, Snow, Bryan, Arya, Sudha, Wong, Jorge, Bouchard, Denis, Binari, Richard, Manoukian, Armen S., Mak, Tak W.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2002
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC123252/
https://ncbi.nlm.nih.gov/pubmed/12172011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172382899
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