The Rho Guanine Nucleotide Exchange Factor DRhoGEF2 Is a Genetic Modifier of the PI3K Pathway in Drosophila

The insulin/IGF-1 signaling pathway mediates various physiological processes associated with human health. Components of this pathway are highly conserved throughout eukaryotic evolution. In Drosophila, the PTEN ortholog and its mammalian counterpart downregulate insulin/IGF signaling by antagonizin...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Chang, Ying-Ju, Zhou, Lily, Binari, Richard, Manoukian, Armen, Mak, Tak, McNeill, Helen, Stambolic, Vuk
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807833/
https://ncbi.nlm.nih.gov/pubmed/27015411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152259
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