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Evidence for a cytopathogenicity determinant in HIV-1 Vpr

HIV-1 is cytopathic for CD4(+) T lymphocytes in vitro and this property of HIV-1 is generally considered to account for some of its in vivo cytopathogenicity. Thus, the extent of lymphocyte depletion correlates with the level of viremia whereas low levels of viral replication are typically associate...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Somasundaran, Mohan, Sharkey, Mark, Brichacek, Beda, Luzuriaga, Katherine, Emerman, Michael, Sullivan, John L., Stevenson, Mario
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2002
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123170/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12093916/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.142313699
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