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Evidence for a cytopathogenicity determinant in HIV-1 Vpr

HIV-1 is cytopathic for CD4(+) T lymphocytes in vitro and this property of HIV-1 is generally considered to account for some of its in vivo cytopathogenicity. Thus, the extent of lymphocyte depletion correlates with the level of viremia whereas low levels of viral replication are typically associate...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Somasundaran, Mohan, Sharkey, Mark, Brichacek, Beda, Luzuriaga, Katherine, Emerman, Michael, Sullivan, John L., Stevenson, Mario
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123170/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12093916/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.142313699
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