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Evidence for a cytopathogenicity determinant in HIV-1 Vpr
HIV-1 is cytopathic for CD4(+) T lymphocytes in vitro and this property of HIV-1 is generally considered to account for some of its in vivo cytopathogenicity. Thus, the extent of lymphocyte depletion correlates with the level of viremia whereas low levels of viral replication are typically associate...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123170/ https://ncbi.nlm.nih.gov/pubmed/12093916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.142313699 |
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