The ryanodine receptor modulates the spontaneous beating rate of cardiomyocytes during development

In adult myocardium, the heartbeat originates from the sequential activation of ionic currents in pacemaker cells of the sinoatrial node. Ca(2+) release via the ryanodine receptor (RyR) modulates the rate at which these cells beat. In contrast, the mechanisms that regulate heart rate during early ca...

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Detalhes bibliográficos
Main Authors: Yang, Huang-Tian, Tweedie, David, Wang, Su, Guia, Antonio, Vinogradova, Tatiana, Bogdanov, Konstantin, Allen, Paul D., Stern, Michael D., Lakatta, Edward G., Boheler, Kenneth R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123122/
https://ncbi.nlm.nih.gov/pubmed/12089338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.142651999
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