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Inhibition of cyclooxygenase 2 blocks human cytomegalovirus replication

Cyclooxygenase 2 (COX-2) mRNA, protein, and activity are transiently induced after infection of human fibroblasts with human cytomegalovirus. Prostaglandin E(2), the product of COX-2 activity, is transiently increased by a factor of >50 in cultures of virus-infected fibroblasts. Both specific (BM...

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Detalhes bibliográficos
Main Authors: Zhu, Hua, Cong, Jian-Ping, Yu, Deborah, Bresnahan, Wade A., Shenk, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122626/
https://ncbi.nlm.nih.gov/pubmed/11867761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052713799
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