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Functional map of human cytomegalovirus AD169 defined by global mutational analysis

Human cytomegalovirus has a complex double-stranded DNA genome of ≈240,000 bp that contains ≈150 ORFs likely to encode proteins, most of whose functions are not well understood. We have used an infectious bacterial artificial chromosome to introduce 413 defined insertion and substitution mutations i...

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Detalhes bibliográficos
Main Authors: Yu, Dong, Silva, Maria C., Shenk, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC218769/
https://ncbi.nlm.nih.gov/pubmed/14519856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1635160100
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