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Functional map of human cytomegalovirus AD169 defined by global mutational analysis
Human cytomegalovirus has a complex double-stranded DNA genome of ≈240,000 bp that contains ≈150 ORFs likely to encode proteins, most of whose functions are not well understood. We have used an infectious bacterial artificial chromosome to introduce 413 defined insertion and substitution mutations i...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC218769/ https://ncbi.nlm.nih.gov/pubmed/14519856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1635160100 |
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