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MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq
Signaling via mitogen-activated protein kinases is implicated in heart failure induced by agonists for G protein-coupled receptors that act via the G protein Gαq. However, this assertion relies heavily on pharmacological inhibitors and dominant-interfering proteins and not on gene deletion. Here, we...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The National Academy of Sciences
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122615/ https://ncbi.nlm.nih.gov/pubmed/11891332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062453699 |
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