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Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival
Cardiac muscle regeneration after injury is limited by “irreversible” cell cycle exit. Telomere shortening is one postulated basis for replicative senescence, via down-regulation of telomerase reverse transcriptase (TERT); telomere dysfunction also is associated with greater sensitivity to apoptosis...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The National Academy of Sciences
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC56957/ https://ncbi.nlm.nih.gov/pubmed/11517337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191169098 |
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