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The Amyloid Precursor Protein Locus and Very-Late-Onset Alzheimer Disease

Although mutations in the amyloid-β precursor protein (APP) gene are known to confer high risk of Alzheimer disease (AD) to a small percentage of families in which it has early onset, convincing evidence of a major role for the APP locus in late-onset AD has not been forthcoming. In this report, we...

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Bibliografiske detaljer
Main Authors: Olson, Jane M., Goddard, Katrina A. B., Dudek, Doreen M.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Human Genetics 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1226076/
https://ncbi.nlm.nih.gov/pubmed/11500807
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