Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues

Human pharmacokinetics data indicate that i.v. ascorbic acid (ascorbate) in pharmacologic concentrations could have an unanticipated role in cancer treatment. Our goals here were to test whether ascorbate killed cancer cells selectively, and if so, to determine mechanisms, using clinically relevant...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Qi, Espey, Michael Graham, Krishna, Murali C., Mitchell, James B., Corpe, Christopher P., Buettner, Garry R., Shacter, Emily, Levine, Mark
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2005
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224653/
https://ncbi.nlm.nih.gov/pubmed/16157892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506390102
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