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Calculated cell-specific intracellular hydrogen peroxide concentration: Relevance in cancer cell susceptibility during ascorbate therapy

The high extracellular hydrogen peroxide (H(2)O(2)) concentrations generated during pharmacological ascorbate (P-AscH(−)) therapy has been shown to exhibit a high flux into susceptible cancer cells leading to a decrease in clonogenic survival. It is hypothesized that the intracellular H(2)O(2) conce...

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Detaylı Bibliyografya
Yayımlandı:Free Radic Biol Med
Asıl Yazarlar: Erudaitius, Dieanira, Mantooth, Jacqueline, Huang, Andrew, Soliman, Jesse, Doskey, Claire M., Buettner, Garry R., Rodgers, Victor G.J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160292/
https://ncbi.nlm.nih.gov/pubmed/29601946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2018.03.044
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