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Doxorubicin increases intracellular hydrogen peroxide in PC3 prostate cancer cells

We studied the effect of doxorubicin on the production of hydrogen peroxide by PC3 human prostate cancer cells, using a sensitive assay based on aminotriazole-mediated inhibition of catalase. PC3 cells exposed to increasing concentrations of doxorubicin had an increase in intracellular hydrogen pero...

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Publicat a:Arch Biochem Biophys
Autors principals: Wagner, Brett A., Evig, Crystal B., Reszka, Krzysztof J., Buettner, Garry R., Burns, C. Patrick
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538991/
https://ncbi.nlm.nih.gov/pubmed/16054588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2005.06.015
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