Llwytho...

The kinase inhibitor imatinib mesylate inhibits TNF-α production in vitro and prevents TNF-dependent acute hepatic inflammation

Imatinib exerts potent antileukemic effects in vitro and in vivo. Despite its well known antitumor activity, the potential of imatinib for the treatment of inflammatory diseases remains elusive so far. Our current report provides strong evidence that imatinib has potent antiinflammatory effects. It...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wolf, Anna Maria, Wolf, Dominik, Rumpold, Holger, Ludwiczek, Susanne, Enrich, Barbara, Gastl, Guenther, Weiss, Guenter, Tilg, Herbert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224614/
https://ncbi.nlm.nih.gov/pubmed/16174751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501758102
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