FHL2 inhibits the activated osteoclast in a TRAF6-dependent manner

TNF receptor–associated factor 6 (TRAF6) associates with the cytoplasmic domain of receptor activator of NF-κB (RANK). This event is central to normal osteoclastogenesis. We discovered that TRAF6 also interacts with FHL2 (four and a half LIM domain 2), a LIM domain–only protein that functions as a t...

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Autores principales: Bai, Shuting, Kitaura, Hideki, Zhao, Haibo, Chen, Ju, Müller, Judith M., Schüle, Roland, Darnay, Bryant, Novack, Deborah V., Ross, F. Patrick, Teitelbaum, Steven L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2005
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224296/
https://ncbi.nlm.nih.gov/pubmed/16184196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24921
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