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Glucocorticoids suppress bone formation via the osteoclast

The pathogenesis of glucocorticoid-induced (GC-induced) bone loss is unclear. For example, osteoblast apoptosis is enhanced by GCs in vivo, but they stimulate bone formation in vitro. This conundrum suggests that an intermediary cell transmits a component of the bone-suppressive effects of GCs to os...

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Bibliografiset tiedot
Päätekijät: Kim, Hyun-Ju, Zhao, Haibo, Kitaura, Hideki, Bhattacharyya, Sandip, Brewer, Judson A., Muglia, Louis J., Ross, F. Patrick, Teitelbaum, Steven L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1518793/
https://ncbi.nlm.nih.gov/pubmed/16878176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28084
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