Inosine 5'-monophosphate dehydrogenase binds nucleic acids in vitro and in vivo.

Inosine 5'-monophosphate dehydrogenase (IMPDH) is the rate-limiting enzyme in the de novo biosynthesis of guanine nucleotides. In addition to the catalytic domain, IMPDH contains a subdomain of unknown function composed of two cystathione beta-synthase domains. Our results, using three differen...

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Hauptverfasser: McLean, Jeremy E, Hamaguchi, Nobuko, Belenky, Peter, Mortimer, Sarah E, Stanton, Martin, Hedstrom, Lizbeth
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224093/
https://ncbi.nlm.nih.gov/pubmed/14766016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031585
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