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Ligand control of interaction in vivo between ecdysteroid receptor and ultraspiracle ligand-binding domain.

Ecdysteroids (Ecs) enhance the formation of Ec receptor-ultraspiracle protein (EcR-USP) heterodimers which regulate gene transcription. To study EcR-USP heterodimerization, fusion proteins were constructed from the LBDs (ligand-binding domains) of Drosophila EcR or USP and the activation or DNA-bind...

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Detalhes bibliográficos
Main Authors: Bergman, Thomas, Henrich, Vincent C, Schlattner, Uwe, Lezzi, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223994/
https://ncbi.nlm.nih.gov/pubmed/14594447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031302
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